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by amysavesjacks on 27 March 2014 - 00:03
Can someone explain to me what this means? I actually did look it up first before asking...
My understanding is that it is the percentage/chance of homozygous allele being passed on to the progeny (at least thats how I understood it and correct me if I am completely wrong).
That being said... I know the desireable traits I would hope to get from this 5-5 linebreeding... but how is one to investigate the undesireable? Please forgive me if this is a stupid question.... And.. I'm not sure I understand the difference between the two scales?
My understanding is that it is the percentage/chance of homozygous allele being passed on to the progeny (at least thats how I understood it and correct me if I am completely wrong).
That being said... I know the desireable traits I would hope to get from this 5-5 linebreeding... but how is one to investigate the undesireable? Please forgive me if this is a stupid question.... And.. I'm not sure I understand the difference between the two scales?
Linebreeding - 5 generations |
Inbreeding coefficient | ||
|---|---|---|---|
| Occurrences | Ancestor | Wright's | Hardiman's |
| 5 - 5 | VA4 2X VA1(USA) Enzo von Buchhorn | 00.20% | 01.81% |
by GSD Lineage on 27 March 2014 - 00:03
| Main |  New linebreeding feature |
80 minutes ago byjc.carroll >> (goto) |
by bubbabooboo on 27 March 2014 - 02:03
I believe the new tool is all about inbreeding and the probability of shared genes and the inheritance of both beneficial and deleterious traits. The problem for those trying to breed for the perfect dog in their dog breed of choice is that gene inheritance and gene expression are two different things. Identical twins are never really identical even though they share the identical DNA and RNA. Subtle differences occur in the womb and in the environment both before and after birth which cause two identical individuals created from the same fertilized egg to grow differently, develop differently, and perhaps have different outcomes during their lives. The fact is that inbreeding can produce remarkable individuals in terms of both desireable and undesireable traits. It is not so clear if inbreeding in the longer view actually changes the occurence of more desireable genes and less desireable genes in the general population over many generations.
by GSD Lineage on 27 March 2014 - 02:03
I like bubbabooboo's post bringing up epigenetics.
A cloned animal or identical twins can be inbred or outcrossed. They are identical to each other genetically, but may have a high or low Inbreeding coefficient. In the case of clones it should be identical to the nuclear DNA donor. In the case of identical twins their DNA will be identical to each other.
You are right amysavesjacks. It is a probability calculator.
A cloned animal or identical twins can be inbred or outcrossed. They are identical to each other genetically, but may have a high or low Inbreeding coefficient. In the case of clones it should be identical to the nuclear DNA donor. In the case of identical twins their DNA will be identical to each other.
You are right amysavesjacks. It is a probability calculator.
| My understanding is that it is the percentage/chance of homozygous allele being passed on to the progeny (at least thats how I understood it and correct me if I am completely wrong). |
by amysavesjacks on 27 March 2014 - 03:03
Thank you for your response.. and for the link to the other forum discussion... it was very helpful. My brain is hurting now ....lol
by Ibrahim on 27 March 2014 - 19:03
My brain is hurting too. I have read all posts here and on the other rhreads, question remains, Is their any study that proves the value of coi ?
Ibrahim
Ibrahim
by dozer911 on 27 March 2014 - 20:03
It's just another tool in the toolbox...
You don't base you decisions on the COI calculator, but it can give you an overwiev of how tight a dog is bred.
You don't base you decisions on the COI calculator, but it can give you an overwiev of how tight a dog is bred.
by guddu on 27 March 2014 - 22:03
In simple terms, if coi is high, it means more inbreeding that will give you a higher probability of the good and bad from the dog in question. So ideally you want to use this information with other info about the dog's good traits and bad traits. The COI has been applied to reduce incidence of hip dysplasia in dogs amongst other things.
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