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by Doppelganger on 23 February 2011 - 15:02
The Flatcoated Retriever Society are holding a health seminar at Stoneleigh on 5th June and one of the items on the agenda is JRD. Here is a link to an interesting article on it:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016684
Thought this might be of interest.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016684
Thought this might be of interest.
by Doppelganger on 23 February 2011 - 15:02
by Videx on 23 February 2011 - 19:02
GSD breeders would be very well advised to look very carefully at the very high incidence of JRD in Flat Coated Retrievers (FCR) to see how JRD can become rife in a breed.
by Videx on 25 February 2011 - 11:02
THE ORTHOPEDIC FOUNDATION FOR ANIMALS
CURRENTLY AVAILABLE DNA TESTS - INCLUDING RENAL DYSPLASIA
http://www.offa.org/dna_alltest.html
Renal Dysplasia in the following breeds
Bernese Mountain Dog, Bichon Frise, Boxer, Cairn Terrier, Collie, English Cocker Spaniel,
German Shepherd, Golden Retriever, Gordon Setter, Havanese, Lhasa Apso, Miniature Schnauzer, Poodle, Portuguese Water Dog, Shetland Sheepdog, Shih Tzu, Soft Coated Wheaten Terrier, Tibetan Terrier, Weimeraner
by Abby Normal on 25 February 2011 - 11:02
That sounds like an incredibly interesting seminar, and there are several items on that agenda that really interest me, thanks for that.
I understand that there have been problems with faulty results for flatcoats with the JRD test, and you have to bear in mind that this test is still in the research stages. Last I heard flatcoat breeders were re-submitting their results, since a 'wild gene' appeared to have been discovered. Perhaps they have addressed this in the test now, and will cover it in the seminar. I believe FCR breeders were re-testing, but I don't know what the outcome was as yet.
Also, what I think is currently problematic is that there is no requirement for identification for the test, since it is sent directly to DogGenes by the owner/breeder. IMO, this method must be changed, and the test and identification undertaken at a vet surgery, and sent for testing by the vet to maintain the integrity of the test.
I do know of 1 GSD that had this and died at age 4. It was heartbreaking.
I understand that there have been problems with faulty results for flatcoats with the JRD test, and you have to bear in mind that this test is still in the research stages. Last I heard flatcoat breeders were re-submitting their results, since a 'wild gene' appeared to have been discovered. Perhaps they have addressed this in the test now, and will cover it in the seminar. I believe FCR breeders were re-testing, but I don't know what the outcome was as yet.
Also, what I think is currently problematic is that there is no requirement for identification for the test, since it is sent directly to DogGenes by the owner/breeder. IMO, this method must be changed, and the test and identification undertaken at a vet surgery, and sent for testing by the vet to maintain the integrity of the test.
I do know of 1 GSD that had this and died at age 4. It was heartbreaking.
by Videx on 25 February 2011 - 13:02
Far too many GSD are dying as a result of this disease. The FCR breed and a few other breeds have very serious levels of incidence of this disease, to such an extent that the carriers seriously outnumber the clears. I hope our GSD breed is not heading in that direction. My Kennel certainly isn't.
LATEST INFORMATION OF RENAL DYSPLASIA
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016684
LATEST INFORMATION OF RENAL DYSPLASIA
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016684
by Abby Normal on 25 February 2011 - 15:02
Videx
Out of curiosity what numbers of GSD are recorded as dying from JRD, and where is that information available ?
Out of curiosity what numbers of GSD are recorded as dying from JRD, and where is that information available ?
by NikkiF on 25 February 2011 - 16:02
Abbey Normal - 2 females out of my 'A' litter who were diagnosed as carriers (one a double carrier) both had to be put to sleep before 18 months of age with JRD related problems. Both have been replaced but it was devastating for both lots of owners. 6 out of the litter of 8 tested as carriers - 2 of those tested as double carriers. Mother of the litter also diagnosed as a carrier is still fit and well at age 8 and none of the other puppies have shown any sign of illness but 2 is 2 too many! All my current breeding stock have tested 'clear' for JRD and I would urge anyone who has the slightest doubt to get the test done.
Nikki Farley
Nikonis GSD
Nikki Farley
Nikonis GSD
by Abby Normal on 25 February 2011 - 17:02
Nikki
That's terrible for you, and dreadful for dogs and owners. As I said before I know of one dog who lived until he was 4 then died from this. He was a beautiful dog and it was tragic. I agree 2 is 2 too many. I always advocate that all available health testing for genetic diseases is used.
If I were breeding, I would have the test done, and I am aware that you use the health tests available. So glad to hear you now have clear stock.
There has however been a problem with the test, which I am hoping is now resolved. My question was, is this information recorded anywhere, and do we know how many GSD have been affected/diagnosed as clear or carriers, a database of results if you will.
I have always 'heard' that incidence of JRD in the GSD are very low, but do not know what that statement is based on, hence the question.
That's terrible for you, and dreadful for dogs and owners. As I said before I know of one dog who lived until he was 4 then died from this. He was a beautiful dog and it was tragic. I agree 2 is 2 too many. I always advocate that all available health testing for genetic diseases is used.
If I were breeding, I would have the test done, and I am aware that you use the health tests available. So glad to hear you now have clear stock.
There has however been a problem with the test, which I am hoping is now resolved. My question was, is this information recorded anywhere, and do we know how many GSD have been affected/diagnosed as clear or carriers, a database of results if you will.
I have always 'heard' that incidence of JRD in the GSD are very low, but do not know what that statement is based on, hence the question.
by Doppelganger on 25 February 2011 - 18:02
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