What is a "Purpose Bred Dog" used in research - Page 1

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bubbabooboo

by bubbabooboo on 31 May 2016 - 16:05

For those not willing to read the research reports which are the basis of the "safety" testing for many of the pesticides ( heartworm ) and other chemicals added to our pets diets or used as pest control agents you will find the term "purpose bred dog". Another one of the lies and purposeful misrepresentations that FDA and the government allows the pharma and pest control industry to visit upon our pets in the form of untested at best and unsafe at worst products which our pets receive. Purpose bred dogs are lab lines of dogs bred for generations for use in lab tests. In many cases beagles and there are different versions. Want to test a macrocyclic lactone ( heartworm ) there are ones that can tolerate high rates ... it really helps to use test animals which can tolerate your products better than the general population of dogs when you need to establish safety. The contractors and companies know the traits of these "purpose bred dogs" and can pick one that increases the likelihood that their products will pass the tests. Links below to some companies selling "purpose bred dogs" for research. In many if not most of these research trial the dogs are killed either for post mortem dissection or when they are no longer needed.  Leave no evidence or the possibility of further testing.  This is one way in which a product tested safe can sicken or kill your dog.  The tests are rigged.

https://www.marshallbio.com/marshall-beagler

Marshall Beagle®


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For over 50 years the Marshall Beagle® has contributed to the safety and efficacy testing of new medicines and therapies for both humans and animals. The colony was established in 1962, and was officially closed in 1967.

Please contact us for pricing or for more information about availability of Marshall Beagles® in your region. Login to our site under Customer Access to access our background data.

http://www.beaglefreedomproject.org/beagles_bred_at_two_dane_county_facilities_go_to_labs_around_the_country

http://www.beaglefreedomproject.org/right_to_release


by duke1965 on 31 May 2016 - 17:05

if im correct hoechst germany also had their own breeding program of heavily inbred beagles, dont know if they still do

by joanro on 31 May 2016 - 18:05

I don't use 'new' heartworm products. I've been using the same preventative for 34 yrs. I only administer every other month during warm weather seasons, have never had a dog test positive for heartworms....not since a dog I owned forty years ago, before preventatives, had huge infestation of heartworms at only 4 yr of age. Treatment was lengthy, since his lungs and heart were infested....he got to the point where walking ten feet would cause his tongue to turn blue and he'd keel over, passed out. It took months of innovative treatment taking him to the vet every day. I had to spoon feed him every hour one tablespoon of food at a time, because his liver was so enlarged from the med and worms, his stomache could not hold any more at a time....it took six months, but he recovered. Never again,since preventative came on the market, will another dog of mine get heartworms.


bubbabooboo

by bubbabooboo on 31 May 2016 - 18:05

The thread is to focus attention on the way the drug and pesticide corporations run their tests for animal tolerance and safety for new products. The devil is in the details and a seemingly unimportant reference to purpose bred dogs peels back the veil on the ugly face of an industry swimming in deceit and lies about how products are tested and what those tests really mean. The FDA allows the corporations to do what they want and the corporations have experts who know how to rig the game.

off subject somewhat but Joanro .. your heartworm program is ideal .. I assume ivermectin or one of the macrocyclic lactones is the treatment. Less is more with heartworm control. Monitor the dogs yearly ( SNAP test ) and treat only during months the dogs can get heartworms which in NC is only about six months per year. If anyone can go to their vet without being asked if you need heartworm meds good luck .. and they want to sell you 12 month per year protection. There is no protection or preventative for heartworms in dogs or cats .. all the products for use in dogs and cats are systemic bloodborne meds that are poisons which kill the baby heartworms once your dog is infected and the poison is in your dog's system 24/7 during the months the animal receives treatment. The reason the vets and drug companies love heartworms is that the true cost per dog is around 15 cents ( 65 lb dog ) at full retail price that the same product is used in cattle or sheep. Vets love prescription heartworm products as they get an office visit and a sale from each use or prescription.

There also reason for concern about drugs and pesticides that can damage the blood brain barrier as research indicates that once the blood brain barrier is injured or diseased other neurologic disorders and diseases such as DM can occur as a result.

bubbabooboo

by bubbabooboo on 31 May 2016 - 19:05

It would be a mistake to underestimate the complexity and specific purposes of the dogs bred for research. The breeders who supply these dogs have different "products" for different clients to satisfy their "needs". These are scientific breeding programs with parental lines and the "lab" products can be tailored to the clients desired result requirements. There are some states with laws protecting lab animals from being killed after they are "retired" and some organizations that handle rescue and adoption for these lab animals. Usually all of the " treated " animals are killed but the "checks or untreated" can be recycled or adopted out. Unless protected by laws most of the lab animals are killed when no longer of use. Those who have adopted lab strain dogs have not reported any unusual health problems but social and training problems are common as the dogs have spent their entire lives in small cages or rooms. The requirement is that the dog must be given room equal to the square of the animals length plus 6 inches. Beagles are small thus they require perhaps 10-15 square feet per animal. It is not clear which agencies enforce these rules or if they are enforced at all.

https://www.marshallbio.com/mongrelshounds

Mongrels/Hounds


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Marshall BioResources provides a variety of mixed breed mongrels and hounds. All of our dogs are born and raised at our Class A breeding facility, and are purpose-bred for biomedical research. Our mongrels and hounds have contributed significantly to the development of new veterinary medicines and vaccines, often marketed for pets. These dogs have also been valuable for understanding human and canine cardiovascular disease and skeletal development. In addition, our mongrels and hounds have played an integral role in the development of new medical devices and surgical procedures, such as heart stents and artificial joints.

Please contact us for pricing or for more information about availability of mongrels and hounds in your region. Login to our site under Customer Access to access our background data.


by joanro on 31 May 2016 - 19:05

I guess success rate over a 34 yr period speaks to 'testing'. If its about using animals to lab test, how else can they learn. Not saying I like the thought of lab animals, but I also don't like what happens to beloved animals when there are no meds developed for stuff like heartworms.

bubbabooboo

by bubbabooboo on 31 May 2016 - 19:05

Off the subject

From American Heartworm Society web pages  ..... "For a variety of reasons, even in regions of the country where winters are cold, the American Heartworm Society is now recommending a year-round prevention program. Dogs have been diagnosed with heartworms in almost every county in Minnesota, and there are differences in the duration of the mosquito season from the north of the state and the south of the state. Mosquito species are constantly changing and adapting to cold climates and some species successfully overwinter indoors as well. Year-round prevention is the safest, and is recommended.  Remember too that many of these products are de-worming your pet for intestinal parasites that can pose serious health risks for humans."

I assume one of the reasons is billions of dollars in profits??  There is no prevention .. the insecticide circulates in your dog's body.  There is no heartworm development once minimum daily temperatures dip below 57 degrees F.  Eighty degrees during the day and 50 degrees at night .. no heartworm transfer from mosquitoes to dogs possible.

Part of your success Joanro may be due to your not following label directions or believing the lies from the American Heartworm Society which is a front organization funded by and for the heartworm insecticide makers.  Researchers know how to rig the test for their benefit. Testing safety of a new drug on a lab strain of dogs which may be more resistant to the toxic effects of the drug is not a true test of safety. Beagles and hounds are much more resistant to macrocyclic lactones than the herding breeds which include the GSD. In the case of the ProHeart6 recall in 2004 the product was injected into 17 million plus dogs at a profit of a two billion dollars to Wyeth and the veterinarians. The FDA narrowly 8-7 forced Wyeth to withdraw the product in 2005 but quietly allowed sales to begin again in 2008. Dogs are still dying and many have growths at the site of injection as the product contains plastics or glass nanoparticles which cause damages to the tissues at the site of injection. A few billion dollars will buy a lot of lies. My GSD had a toxic reaction to ProHeart6 but the veterinarian was so giddy with the profitability of the product in terms of scheduled office visits for injections and kick backs from Fort Dodge and Wyeth that my concerns were dismissed. I never gave my GSD a second treatment of ProHeart6 but for six months she had that toxic material in her body. Later she had cancer. None of these very profitable macrocyclic lactone products have ever been tested for long term health effects.

http://www.dogsnaturallymagazine.com/heartworm-medication-part-1-truths-omissions-and-profits/

http://www.dogsnaturallymagazine.com/heartworm-medication-part-2/

http://news.vin.com/VINNews.aspx?articleId=24469






 


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