Coccidia BAYCOX - Page 1

Just wanted to give an update.  
Had previous problems with coccidia in puppies.  Always done the Albon and it helped somewhat but Coccidia always returned.

I have used Baycox in my past 3 litters and I am happy to post that NONE of my puppies had coccidia AT ALL!  Not even when they went to their new home.

Here is something I copied.

Quote: (1) Institut für Parasitologie, Bünteweg 17, 30539 Hannover, Germany, DE  (2) Bayer AG, 51368 Leverkusen, Germany, DE  (3) University of Veterinary Medicine, Komenskeho 73, 04001 Kosice, Slovak Republic,  Abstract Coccidia of the genus Cystoisospora cause mild to severe diarrhoea in dogs. The effects of toltrazuril treatment on cystoisosporosis were studied under experimental and field conditions. Twenty-four puppies were experimentally infected each with 4 × 104 oocysts of the Cystoisospora ohioensis group. Three groups of six puppies were treated 3 dpi with 10, 20 or 30 mg/kg body weight of toltrazuril suspension (5%); the remaining six puppies served as non-treated controls. Toltrazuril suspension or microgranulate were given once in a dose of 10 or 20 mg/kg body weight, respectively, to naturally infected puppies in conventional dog breeding facilities, depending on the coproscopical evidence of infection. Oocyst excretion and clinical data were recorded. Under experimental conditions, the non-treated puppies excreted oocysts beginning at 6 dpi and suffered from catarrhalic to haemorrhagic diarrhoea. On 12 dpi, four of six non-treated puppies died. Irrespective of the dose, toltrazuril treatment totally suppressed oocyst excretion and no diarrhoea or other signs of disease were observed in the treated groups. Natural Cystoisospora infections were regularly found during the 3rd or 4th week of age in dog breeding facilities although not always associated with diarrhoea. A single oral application of toltrazuril abrogated oocyst shedding and the treated puppies remained generally coproscopically negative during the following 2–4 weeks. Cystoisospora is pathogenic for puppies and can induce severe disease. Natural infections are common in conventional dog breeding facilities. Toltrazuril treatment is suitable for controlling cystoisosporosis under experimental and field conditions. A single oral treatment for puppies in the 3rd or 4th week of age is recommended.  Received: 2 February 2000 / Accepted: 4 February 2000

The actual Baycox site: http://www.baycox.com/

[/quote]CALL FOR ABSTRACTS 

DEADLINE APRIL 30, 2008 

Use of toltrazuril (BAYCOX®) to treat Cystoisospora spp. infections in a SCID dog colony 
T. J. NOLAN*1, M. L. CASAL2, P. O’DONNELL2, R. MARCANTUNO1, AND P. J. FELSBURG2. 1DEPARTMENT OF PATHOBIOLOGY AND 2DEPARTMENT OF CLINICAL STUDIES, UNIVERSITY OF PENNSYLVANIA SCHOOL OF VETERINARY MEDICINE, PHILADELPHIA, PA. 

Species of the genus Cystoisospora (syn. Isospora) can cause severe diarrhea in some infected dogs, especially dogs lacking immunity to the parasites. The only FDA approved drug for treating the enteritis associated with coccidiosis in dogs is sulfadimethoxine. However, this drug is a coccidiostat, and thus, elimination of the parasite depends on the immune response of the dog. In our breeding colony of Severe Combined Immunodeficiency dogs (which lack B and T-Cell responses) treating coccidial infections with a coccidiostat has been problematic. In addition, these dogs suffer from recurrent Giardia and Campylobactor infections which result in frequent bloody diarrhea and death if not treated appropriately. We reasoned that treatment using a coccidiocidal drug would improve health and management of the SCID dogs. There have been several reports on the use of the coccidiocide toltrazuril in dogs for the treatment of Cystoisospora spp. Therefore, we evaluated this drug for treatment of clinical coccidiosis in our colony. Dogs identified as infected with C. canis, C. ohioensis or C. burrowsi were treated with one oral dose (20 mg/kg) of toltrazuril and fecal samples were examined by the zinc sulfate centrifugation technique for the next 3 to 5 days for the presence of oocysts. Oocysts rapidly disappeared from the feces, with 67% of the dogs becoming negative by 2 days post-treatment. No adverse effects were seen in any of the treated dogs and the overall health of the SCID colony improved after treatment with toltrazuril was begun. Toltrazuril had no activity against Giardia. 



 

Good info and experience to share. Thank you. 

I did something similar -- I used "Ponazuril"--it's a similar medicine. I showed my vet some literature about it, she did some research, then  had a compounding pharmacy make it for me. Very reasonable cost and extremely effective and seems to be easy and safe for puppies.

http://www.springerlink.com/content/dk305576265465q3/?MUD=MP

http://www.crbeagles.com/misc/coccidia.htm

Christine