should I have my dog tested for exocrine EPI - Page 1

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by cyneye on 18 March 2008 - 18:03

My older German Shepard is showing what I think could be some signs of EPI and I have asked my vet to due the TLI test which he says is $110. However, I read on the internet that  exocrine pancreatic insufficiency in the GSD is typically presented in young adult dogs between 1 to 5 years of age. My dog is age 12 and has had  problems with intermittent diarrhea for 5 years...we have ruled out worms and for the past two years have had her on Canidae natural pet food (human grade) and now Natural Balance  grain free venison and sweet potato food to rule out food allergies but she still gets bad diarrhea on and off. She has had extensive treatment for months with metronidazolel which does help  but then the diarrhea comes back. We recently started giving her Prozyme and this seems to helps. She is losing weight , is hungry all the time, eats other dogs and cat poop any chance she can but not her own, has gut sounds, her coat seems dry, brittle and she has dandruff. ...and she has intermittent diarrhea and foul smelling "cow patty" feces. Do you think I should continue to push my vet to due the TLI test?
 


by hodie on 18 March 2008 - 18:03

What you describe is certainly suggestive of some sort of pancreatic/gut dysfunction. There are a lot of things you might try first. I have a lot of experience with dogs who have the kinds of problems as you mention your dog has. Feel free to email me privately and I can ask you some specific questions and perhaps provide some things to try. 

Doing the test will give you more information, but it is likely to result in your trying some of the things I and others might suggest in any case. So I might try some things before I shelled out the cash. 

By the way, pancreas problems, just like other health issues, can surface at any age. They most commonly present in a dog over 3 years in my experience, but older dogs can begin to have trouble too as the pancreas looses the ability to consistently produce the correct kind and amount of enzymes necessary for digestion.

schwarzenberggsd@earthlink.net


tigermouse

by tigermouse on 18 March 2008 - 19:03



we thought out bitch had EPI.

after many blood tests and visits to the vet we discovered it was not EPI but a vit B deficiency 1 shot of vit B for 4 weeks and she was fine not a problem since.  be very careful when TLI tests are being done as the can give false results if taken when the dog has the runs...

 


flygirl55

by flygirl55 on 18 March 2008 - 22:03

Sounds alot like EPI. I too have an EPI dog. We went through the rounds of all the conventional treatments until I went to a new vet and she did the TLI.  Unfortunately by the time that was done, my girl was down to 53 lbs...not good at all. To echo tigermouse, yep, $110 is a lot but these dogs lose ground very quickly and the faster you find out, the faster you can get her started on enzymes and find the diet that works for her. Also - take a look at the Yahoo users group for EPI dogs - nice people and great resources to use.

Best of luck. Let us know if we can help....


by hodie on 18 March 2008 - 23:03

 Based on private communication between the original poster and myself I do not now think this is related to EPI or a pancreas problem. Such health issues exhibit very characteristic signs, none of which his dog has, except for occasional loose stool. Color is not right. The dog was treated in the past with medications that indicate an irritable bowel and/or bacterial infection. I gave him some ideas to try.

Whenever such conditions appear, it is absolutely imperative to rule out first a myriad of other generally simply solved problems, including parasites, fungal or bacterial infection. Otherwise, one just goes round and round in a viscous circle and it becomes increasingly difficult to figure out the real problem. There is certainly nothing wrong with doing TLI, but in my opinion, it should not be the first thing tried. I am convinced some dogs have transient problems which can even show up on TLI and then they get an incorrect diagnosis and nothing helps because the problem has not been correctly diagnosed.


by Sabre Excalibur on 12 February 2009 - 08:02

Although this post is old, it raises an important question.  The majority of dogs with Exocrine Pancreatic Insufficiency (EPI) are GSDs.   An excellent website called "EPI in Dogs" describes in simple terms the symptoms, diagnosis, management, etc.  It's at www.globalspan.net/epi.htm .  

Texas A&M University is currently doing research to identify the genetic markers for EPI which could help eliminate this terrible disease.  They still need at least 40 purebred GSDs who have EPI to donate blood for the study.  If you know anyone with a GSD that has EPI, please have them click on the link in the red text on the webpage above for details.  No pedigree documents are needed.  Most vets will draw the blood for free since it's for a great cause.  How wonderful it would be if the genetic markers could be identified! 

Just wanted to spread the word.  Although EPI affects GSDs more than any other breed, no breed is immune.  In fact, it's now even seen in mixed breeds with no relationship to shepherds.

By the way, the link above also talks about Small Intestinal Bacterial Overgrowth (SIBO) and cobalamin (B12) deficiencies, both of which can often affect EPI dogs. 

Renofan2

by Renofan2 on 13 February 2009 - 01:02

I was wondering if anyone else with EPI dogs experienced problems trying to use the generic viokase?  I went thru two bottles of viokase and switched Molly's food to Solid Gold Wolfking, then tried biocase as it was alot  less expensive and came recommended.  Molly seemed to do well on the viokase but now I am noticing weight loss again and her fur is falling out in clumps since switching to the biocase.   I just picked up another bottle of viokase and will start her back on it on her next meal, but wanted to know if others have experienced this as well.  When I phoned my vet this morning he told me that his epi dog only seemed to do well on viokase.  He also tried various generics as well as raw pig pancreas but never had success.  I leave the enzymes on her food for about 20 minutes.  Is that enough time or should I leave it on the food longer?

Any advice would be appreciated.

Cheryl

by My Guy Kai on 13 February 2009 - 01:02

Viokase is good if you're using the powder.  The pills don't seem to work well.  I've used Pancrezyme, which is expensive, and am now using the stuff from the Yahoo! EPI group... it's call Pancreatin.  It's a lot cheaper, and I can't tell the difference.  My dog does great on both.

All of these enzymes are rather finicky... they can vary from batch to batch, and if they get too hot (from being left out on the counter in the sun, or during shipping) they begin to lose their effectiveness. 

Letting the enzymes sit for 20-30 minutes is recommended by many, but most vets say you don't need to.  It seems that every single EPI dog I know is so very different from all the others, that if it works for you, do it.  If not, try something else.  I usually wait a week after changing something, but can usually tell within 2 days if it's working for my dog or not.

I take it this is a rather new diagnosis for you?  :)

Renofan2

by Renofan2 on 13 February 2009 - 02:02

Yes, new diagnosis.  Molly was diagnosed in December and turned 3 last week.  She is barely 50 lbs as this point and never experienced the shedding like she has had over the past 3 weeks.   She also was diagnosed with Sibo so is also on Tylan powder -1/4 tsp per day with viokase.  Trying to decide if I should  keep her on Solid Gold Wolfking or switch to Wellness Core.  I guess I will just have to be patient and adjust everything when it stops working.  She did so well on the viokase and just hope that she does as well when I swtich her back.

I have requested information from my qc/r&d department in the netherlands as my company is the manufacturer of Lipase, protease and amylase that goes into viokase.  Never know what one can find out from the inside.

Cheryl


by Sabre Excalibur on 13 February 2009 - 06:02

Hi Cheryl.  Sorry to hear Molly's been diagnosed with EPI, but we've learned if you do the right things, it's really quite manageable.  Did you get a chance to look at  www.globalspan.net/epi.htm?  I think it answers almost all your questions.  It's set up in a really easy-to-understand way too. 

We're members of the K9-EPIGLOBAL Yahoo Group too.  (You can reach it via the link above.)  I highly recommend joining.  The advice is wonderful and everyone is so helpful!  We switched from Viokase-V powder to the Pancreatin 6X powder and never noticed any difference (except a HUGE cost savings).  We haven't had any problems with the enzymes, temperature-wise.  The link above explains how they should be stored and explains how long to soak enzymes to avoid problems. 

We're fighting SIBO too.  It's my understanding that Tylan is usually given twice a day, but maybe Molly's needs are different.

Good luck! 

P.S.  Please consider donating Molly's blood through your vet for the Texas A&M EPI research project.  They still need 41 purebred GSDs with EPI to donate.  Thanks!

 

 






 


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