research into DNA markers for HD? - Page 1

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anika bren

by anika bren on 11 October 2004 - 21:10

Does any one know if there has been any research done to find the genetic markers for HD, ED and other genetic diseases on the canine genome? I know in horses they are able to DNA test to find genetic diseases, i.e. HYPP, Lethal White etc. Owners are able to test horses before they are bred to see if they carry these recessive genes. If there has been, would someone guide me to a website that discusses the findings? If there hasn't been any such research done, I would sure like to start getting people together to discuss the subject and maybe find a way to get the research started.

by Het on 11 October 2004 - 22:10

check the AKC site they have been working on this for a few years now. Heather

by Trini to the Bone on 12 October 2004 - 05:10

The SV is currently doing work on this area and is close to or have already identified the genes which causes the HD in the canine genome. These studies are very recent and will be very promising for the COMPLETE eradication of HD in future.

by Preston on 12 October 2004 - 06:10

Yes this is now underway at a top university vet research school (I can't recall the name, OFA may know). It is related to the total gene mapping of a certain sporting dog which I can't remember the name of (a type of setter or retreiver). The project is more than half-way to completion and is concerned with identifying many serious genetic flaws not just HD. My guess is that these gene locations will apply to all domestic dog breeds.

by Sarek on 13 October 2004 - 01:10

There are several universities and research institutions working on the canine genome map. Partial results have already allowed researchers to begin mapping certain loci for a variety of genetic disorders. Two markers for Progressive Retinal Atrophy have already been identified. This is a link to a project at Berkeley: http://mendel.berkeley.edu/dog.html

anika bren

by anika bren on 13 October 2004 - 01:10

Thanks everyone. It is very nice to have somewhere to go to ask questions. Sarek- I'll check out that website. It will be nice when we can screen our prosective breeding dogs for the major genetic diseases before they are bred. It is so hard to watch peoples' pets, of sll breeds, waste away. Hopefully soon we will be able to prevent that.





 


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