Epilepsy Do we have a problem - Page 3

I believe the GSD helpline has info on some epileptic lines, I have been led to believe that some are either German imports or from VA /high V dogs, maybe in the light of what has been said on the various threads it is time to give us advise on this matter, it is a really frightening disease, please anyone that has info come forward with it.  

The GSD Helpline no longer exists as far as I'm aware.  I do recall Alyson lockwood having a rather comphrensive list of known epileptic dogs/carriers etc.  It used to be published on the website, but that's been gone for a while now.

CAROL    da ya mean the GSD info group when ya say helpline ?. dorothy cullum as bin saying fer ages she's got all the info on tha dogs ya mention ------- she WONT give out na info ------- says she aint allowed to tell !, so wots the use in her knowin an nobody else !!!!!!.  DARN STUPID !!!!.

sorry yes I  meant the GSD Info group, I dont understand why we cant have the info, if it is fact then it is fact, if hearsay or rumour then yes they should not give out the info.

I have just had  phone calls from both David Bowen and Davey Hall, Both have expressed great concern about this situation, David Bowen tells me Apollo and his many progeny have never produced any Epilepsy.He is also willing to assist anyone who can resolve this problem. Davey Hall has confirmed Nasko is the the sire involved and one other youngster bred by Eddie Armstrong. It  first came to Davey's  notice in October 2008, and Nasko has not been used since. Davey thought Eddie's youngster was an isolated case. Davey has checked with the people in Ireland who have Nasko progeny and there is no problem there. Davey tells me he is in contact with Chris Hazel, and very happy to assist, and supply any information that is relevant to identify the sauce of this tragic situation. This is good news, and hopefully with help from the powers that be, we may isolate and resolve this potential nightmare. I would like to thank both Davids for their great concern over this situation. regards Bill Owen.

PT1 the mode of inheritence of epilepsy is different in different breeds, as far as I am aware it as not been clarified in the GSD and I am awaiting that information. for example: Belgian shepherd (Groenendael and Tervueren).oligogenic with probable single gene with significant influence Homozygotes will be epileptic and heterozygotes have increased risk of epilepsy.
Lagotto Romagnola autosomal recessive
Keeshonds  autonomic simple recessive
Labrador Retriever  autosomal multifactorial recessive
Miniature Wirehaired Dachshunds Autosomal recessive – disease mutation identified
Standard Poodle  Simple recessive autosomal trait with complete or almost complete penetrance.

Epilepsy appears to be a particularly taboo topic and breeders seem to be exceptionally secretive about it - especially in the UK, hence why most of the recent studies have been completed abroad, infact the genetic mutation in the Dachshund and Bassett was found at the Hospital for Sick Children in Torronto.

I can not comment on the Info group as I was removed as a member.
Pam

edited to add it was the worldwide group that my membership is no longer valid

Blerio, of course whether it is a recessive or dominant is important, the mode of inheritance is our main source of tracing where the problem comes from.. The other day you were all set on blaming it purely on the sire. Think about it. Acting like infants with matches is of no use to the breed or its breeders.
Regards
Sue b 

Sue, people can't agree if it comes  through both or single parents, and the thread started to indicate it was more important to decide who was right or wrong about the theory.  All I wanted to establish, we have a problem,let's all agree that,be open, and honest, and get the main players on board. Hopefully thats been achieved now let the boffins, scientists, and  anyone who can come up with the answers deal with it. The only fact is, the sire has at least 2 progeny with the problem, we must start some where. I don't know who the infants are Sue, maybe you could enlighten us. regards Bill Owen

Bill , the sentance was used as a Metaphor, applying to no-one imparticular. So unless the cap fits don't get so defensive. This is not a matter to start petty personal squabbles over, so please refrain from your obsession to have a dig at me. As for people agreeing if it comes from both or single parents all we can do is read what the experts have said and up to now the only expert evidence supplied to us is that it is an Autosomal recessive. If more studies have been done and this thinking has changed I have asked for this information to be supplied to us. You may not consider this important but as a breeder I do, if breeders don't have the mode of inheritance at hand how on earth are they supposed to make informed decisions about anything? So though it might be irrelevent to you, it isnt to me, so I asked and I asked politely, my question was not directed to you and certainly did not need you to make a PS reference to it in your post.
Regards
Sue b
 

Sue, You're post was defiantly addressed to me,I'm obviously not important, and my obsessions will never include you! I'm not a defensive person, I don't give a toss what people think of me, I am not as you say, a petty person, is it possible you have not had a good week on this site, I would not dream of any personal squabbles with you, I think you have embarrassed yourself enough for at least a couple of posts. regards Bill Owen. x