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by jc.carroll on 22 October 2009 - 20:10
I had been doing some research on Crytorchidism (unilateral and bilateral). Genetics and inherited traits happens to be a fascination of mine. I'd been tracing litters from various dogs that had puppies suffering this condition, and I have noticed that it seems to be as often carried by the dam as by the sire.
Obviously, only male pups suffer the condition; but it appears to be carried on the x-chromosome, not the y. One of the females I had been observing produced at least one Crytorchid male per litter, regardless of the male she was bred to. I noticed this with other females I'd been observing.
I was wondering if there was anyone who could point me in the direction of finding documentation on this in-depth; or knew of any studies like this previously done to determine the possibility of Crytorchidism being something that can be passed down through maternal as well as paternal lines.
I'm now quite convinced that the dam is as much a contributer for this condition as the sire.
I am also currently looking to see if it's something that needs to be carried in both parents before it can be expressed in a litter, or if it can be passed on and expressed even if only one parent carries it. For this I need to observe the progeny of a normal dog with Crytorchid full-sibling... and needless to say this is where I start running into problems because of the sheer number of dogs I've been trying to track and sort through; and the generations I have to follow (minimum of 3).
Again, if anyone has any info or leads that could help, please feel free to contribute.
Obviously, only male pups suffer the condition; but it appears to be carried on the x-chromosome, not the y. One of the females I had been observing produced at least one Crytorchid male per litter, regardless of the male she was bred to. I noticed this with other females I'd been observing.
I was wondering if there was anyone who could point me in the direction of finding documentation on this in-depth; or knew of any studies like this previously done to determine the possibility of Crytorchidism being something that can be passed down through maternal as well as paternal lines.
I'm now quite convinced that the dam is as much a contributer for this condition as the sire.
I am also currently looking to see if it's something that needs to be carried in both parents before it can be expressed in a litter, or if it can be passed on and expressed even if only one parent carries it. For this I need to observe the progeny of a normal dog with Crytorchid full-sibling... and needless to say this is where I start running into problems because of the sheer number of dogs I've been trying to track and sort through; and the generations I have to follow (minimum of 3).
Again, if anyone has any info or leads that could help, please feel free to contribute.
by Sherman-RanchGSD on 23 October 2009 - 21:10
There isnt any that I am aware of.. but would be intersting to know if you do find please share...
Luckily it is *condition* not an affliction.. ...
It is said to be more prevelent in particular family lines and yes not souly coming from males.
Debi
www.sherman-ranch.us
www.ironfistcreations.us
Luckily it is *condition* not an affliction.. ...
It is said to be more prevelent in particular family lines and yes not souly coming from males.
Debi
www.sherman-ranch.us
www.ironfistcreations.us
by Kalibeck on 23 October 2009 - 23:10
Sending you a PM. jh
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