Black spot on the tongue! - Page 1

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by brandilynn on 22 October 2010 - 06:10

I have a white swiss shepherd and she has a black spot on her tongue...so I'm not sure if it has anything to do with the right pigmentation for a German Shepherd...since she's all white


yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 07:10

I have never heard anyone say it is a RIGHT  pigmentation for any german shepherd...It is  the dominant Black and red pigmentation coming from the Sire and the dam of the dog...thousands of german shepherds have black spots on their tongue..
It has to do with the spill over of the  chromosone with a name I cannot remember,,that is black and the yellow red and the hair has to be injected with either and when this is absent ,,,and the hair folicule is not injected the mix up is a genetic dilute and this is from both parents to make a white dog...but it is too indepth for me...The reason a black spot is on dogs tongue is the spill over got into the skin portion where no folicule is and you have pigmentation...like where a mask on the face of the white dog is missing....no black was every put there...it did not get injected by natures design...it is gone haywire so to speak....when dogs get bred the pattern of what the sable parent or the black /red parents dishes out   has to be lined up correctly..when there is minus and plus of the wrong equations...you get the recessive genes that all have names...they go the wrong place...no black   so you end up with WHITE>.. but that does not mean   an injection did not happen on the tongue or roof of mouth or even on the legs sometimes....and you have a birthmark ....the spot on a tongue is not called a birthmark..but it is in a sense....
Who are this dogs parents ?  what color are they and the grand parents...came from somewhere???did this dog not come from a parentage of color not white??? The parents of that dog were black /red or a black shepherd...do you hve the pedigree?? Could you post it please...

White is a throw back recessive gene.


yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 07:10

ont'd:

Fundamentals of Hair Pigmentation
Mammalian hair is composed of a strong structural protein called keratin, the same kind of protein that makes up the nails and the outer layer of skin. Hair grows up from hair follicles, which house a group of highly active cells that form pigment and keratin for each hair fiber. olymer called melanpin forA biological pigmenting ms the coloring agents that are injected into hair fibers.

The word melanin is derived from the Greek word for black, and generally refers to two known melanin pigment variations named eumelanin and phaeomelanin. Eumelanin is a brown/black pigmenting polymer and phaeomelanin is a yellow/red pigmenting polymer.

As each hair fiber is constructed in the follicle, eumelanin and phaeomelanin pigments are injected in various formulations and densities of color granules by little pigment factory cells called melanocytes that are co-located with keratinizing cells at the base of each hair follicle. Color granules are keratinized along with the cytoplasm of each hair fiber as it grows from the lower follicle structure before it emerges from the skin layer. Dogs have a variety of genes consisting of many gene loci and alleles located across several chromosomes that regulate where, how and if each hair follicle melanocyte injects eumelanin and phaeomelanin color granules into its growing hair fiber. These genes and alleles are observed to vary from breed to breed.

To go deeper into the modern understanding of the genetics of dog coat color it is necessary to understand some terminology: All dogs have 78 chromosomes, 39 from each parent forming 39 chromosome pairs. Each chromosome pair lines up specific gene pairs, (one from mother and one from father) at a specific location on the chromosome identified as the locus for that gene. (Loci is the plural.) Often a particular gene at a particular locus has two or more variations in the DNA coding they carry. Each variation of that particular gene is called an allele of that gene. Some alleles are dominant and some are recessive where the dominant allele always dictates the action of the gene pair. Recessive alleles can express themselves only when two copies of the recessive allele (one each from mother and father) appear in a gene pair. Some alleles are somewhere in between dominant and recessive and are called incomplete dominants or co-dominants. This means that the trait is seen with just one co-dominant allele copy, but in genotypes that include combinations of co-dominant allele pairs, the phenotype, or resulting physical characteristics, can vary according to the pairing combination. An inherited gene pair trait, half from the mother and half from the father, is called the genotype in the offspring. Two animals whose genes at a particular locus differ by even a single allele are said to have different genotypes. Dominant alleles are denoted by capital letters and recessive alleles are denoted by small letters, for example, E is dominant e is recessive and Em is co-dominant with E.


yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 07:10

The  problem arises in something called   CLUMPING...when it is wrong  this is where the genes get recessed and the white is outstanding..but the black  can get injected into a partial skin patch where no hair is when the mismatch happens and the clumping is not right....


The Wild Type Black Banded Hair aw Agouti allele, when coded at the Agouti (A) gene, regulates the density, distribution pattern and exact color palette of eumelanin (brown/black) and phaeomelanin (yellow/red) hair pigmenting in many wild animals. The aw allele causes melanocytes to vary the formulations and densities of eumelanin (black/brown) and phaeomelanin (red/yellow) pigment granules they inject into each hair during hair fiber production. The unique aw allele coat pattern is distinguished by hair fibers that are banded black at the tip end, changing to a reddish or cream coloration along the mid-section and finally changing back to black near the skin. Over different parts of the body this can impart a color banding appearance along the full length of some hair fibers and near solid color along the full length of other hair fibers.

Alleles of the Agouti (A) gene, which is one of the major coat color determinate genes for the German Shepherd Dog breed, affect not just where, but also whether the eumelanin (brown/black) phaeomelanin (yellow/red) shift occurs hair by hair over an animal’s body. The primary Agouti regulated coat color patterns of the German Shepherd breed are typically categorized as sable, black and tan and solid black, however, these color patterns can vary greatly in color intensity and pattern detail among different breeding lines. The variation of intensity and detail occurs because the expression of alleles at certain gene loci can modify the expression of alleles at other gene loci.

The aw allele is thought to code for the German Shepherd sable (or wolf) coat color pattern, the at allele is thought to code for the black and tan coat color pattern and the a allele is thought to code for the solid black coat color7, 8. Several different Agouti genotypes are possible including: aw/aw, at/at, aw/at, aw/a, at/a, and a/a, where only the recessive a/a genotype can form a solid black coat. The dominance order has not yet been conclusively confirmed through genetic research, but aw is thought to be dominant over at with the a allele recessive to both aw and at. Genetic research has not yet determined with certainty what, if any, other Agouti alleles code for German Shepherd Dog color variations.


YR    

This is only a tiny look into this study....

yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 07:10

White (German/Swiss) Shepherds Carry Colored Coat DNA
DNA research at the University of Saskatchewan has shown that dogs carrying cream to white colored coats from several breeds, including white coat dogs from German Shepherd breed lines, always have an e/e genotype at MC1R. The Agouti (A) gene aw, at and a alleles, that e/e genotype white coat German Shepherd Dogs# continue to carry, are hidden, or masked. The alleles are hidden because neither phaeomelanin nor eumelanin is made in the hair follicles giving Agouti (A) gene aw, at and a alleles nothing to regulate, and no eumelanin (brown/black) and phaeomelanin (yellow/red) pigment to inject into the growing strands of hair.

The successive white to white breeding programs that formally established the White Shepherd and White Swiss Shepherd breed(s) have "fixed"+ the e allele (and e/e genotype) at the MC1R gene locus, but the Agouti color coat alleles remain hidden in the DNA. Only a potential for the "melanistic" eumelanin black face mask color pattern has been eliminated from fixed e/e genotype White (Swiss) Shepherd and White German Shepherd breed lines. However, a single pairing of a White (German/Swiss) Shepherd dam of genotype e/e - aw/aw with, for example, a Em/Em - aw/aw genotype standard color German Shepherd Dog will produce a litter of Em/e - aw/aw full sable colored German Shepherd puppies with "melanistic" eumelanin black face mask that would be competitive in the prestigious AKC Westminster Kennel Club dog show. A simple breed type DNA test on a White (German/Swiss) Shepherd (Berger Blanc Suisse) dog would return “German Shepherd Dog” as the probable breed type because the dog carries Agouti (A) gene aw, at or a alleles.

# - White Shepherd and Berger Blanc Suisse (White Swiss Shepherd) breed lines were established from White German Shepherd Dog breed lines during the last quarter of the twentieth century and, therefore, would be expected to carry the e/e genotype as well as the complement of hidden Agouti (A) gene alleles. See Wikipedia Encyclopedia for "White Swiss Shepherd."


+ - An allele for which all members of the population are homozygous, so that no other alleles for this locus exist in the population.



This table shows the combination of displayed and hidden white/cream and AKC breed standard colors that are possible in the various e genotypes of the German Shepherd Dog.

MC1R (E)
Genotype Agouti (A)
Genotype Coat Color and Pattern Displayed Hidden Color and Pattern Breeding Potential
Em/e ax/ax sable or black-and-tan w/mask white, lack of mask
Em/e ax/a sable or black-and-tan w/mask white & solid black, lack of mask
Em/e a/a solid black (mask not seen) white, lack of mask
E/e ax/ax sable or black-and-tan white
E/e ax/a sable or black-and-tan white & solid black
E/e a/a solid black white
e/e ax/ax white sable & black-and-tan
e/e ax/a white sable, black-and-tan & solid black
e/e a/a white solid black
note:
ax - denotes the Agouti (A) gene alleles aw for sable and at for black-and-tan
a - denotes the Agouti (A) gene allele for solid black
E - denotes MC1R (E) gene dominant allele for eumelanin extension
Em - denotes the MC1R (E) gene allele for eumelanin extension and face mask pattern
e - denotes the recessive allele for eumelanin off.
Alleles of the Agouti (A) gene were genetically identified through a collaborative research project between the laboratories of Dr. Greg Barsh at Stanford University and the Dr. Sheila Schmutz at the University of Saskatchewan. Unfortunately, commercial DNA test commonly available as of Fall 2007 can not differentiate between the Agouti aw and at (and other possible Agouti) alleles,

yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 07:10

The best explanation I've heard came from one of my med school profs and stipulated that mucous membranes in both humans and canines contain pigment producing epithelium. However, it's activity is subdued in people, but not in dogs, so a black spot on the tongue should be considered akin to a birthmark



epithelium

in anatomy, layer of cells closely bound to one another to form continuous sheets covering surfaces that may come into contact with foreign substances. Epithelium occurs in both plants and animals


Epithelium happens for secretion, protection and  coating of skin   when it is disrupted or formed wrong...color can get stapled to it and forms that spot...small or big or like a freckle.
Laymans   description of it..not a medical or scientist words...too much for me..to spell or figure out how to say it any better.

Hemangiomas and Vascular Malformations of a kind...sorta...lol





melba

by melba on 22 October 2010 - 11:10

Wow, YR. I think I need some more coffee before attempting to read that again. LOL

Melissa

yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 17:10

Well Melba, I didnt study this when I was YOUNG...so I have read and re  read this many times since I got into GERMAN shepherds....
Jane Stephenhagen  had me read books on this and I got so bored and confused but I did..


I had the same happen to me as the other poster...A vet in Dallas Texas told a new customer of Mine with a GORGEOUS pup out of Bear Jerome   the dog I just posted pedigree on the thread about PAN THROWER>>>

Of course we have heavy sable in that pedigree  and black and red that are very DEEP in pigmentation....so  this woman calls me on Mothers Day SUNDAY and says I sold her a mixed breed puppy that has CHOW in it....I came unglued

My pine trees are 300 to 700 feet in the air at my place  ...my blood pressure went way above that...She also said a man in her apt complex told her  the same thing...FUNNIER than goats poop was that same man has one of my german shepherds also.....and he was training him for a cadaver dog...

He told her " you got screwed."  He had no clue who sold her the dog....

Office workers of her husband had told  him the same thing earlier in the week...SO she said   You are a very unreputable breeder and here we were told you were a CHRISTIAN  and well known in this area...bulll  she said..we want our money back and all the vet research done....what research done..I ask....the vet says he can prove it is not a full bred shephred....ha ha ha....Well I hope the  Dr and his wife who Bred Bear was ready for that one...Funny thing ws.....DNA does show parentage but back in a long generation it will not tell you......there is a chow there....how funny...

I got ahold of Jane and she laughed for 10 mins..She called the lady and in her expert breeding language explained  German Shepherd  geneology....and a bit about genetics....

She then called me and had me start reading...3000 of Janes progheny have pups or parents or relative with black spots on their tongues...she had 1500 of them here in usa...

The lady still did not believe me....I told her   Enjoy that gorgeous Hershey you have and do not ever  start this myth again or I will take you to court for defamation of MY character..You need to find facts and talk to german breeders in Germany not the USA and find people who are experts not  off the wall   FLAME THROWERS<<<<<

So yes,,I  an no a math person period  so with that being said....to understand formulas and genes of this EEE and AAA or aaa or eee and try to put it in my BRAIN>>>>>no way...will not ever happen..Just tell me in lay language what it means...........


I ,of course, have no reason to worry about WHITE in my breedings..but I do have to worry about BLUE and LONG COAT>...URAN   has known carrier for both.....and so did JADA V Steffenhaus who is the gr sire of Dieter my main stud after I lost KONIG to a thief...

This is another good thread and studying the   possibilities of  a WHITE or  birthmarks  or how we may have a mutation or a throw back reccessive in any of our lines....blue,  black....cream  or such is worth studying....


I am not learned on this...but I have enough knowledge to keep my eyes on pedigrees and ask a GERMAN well learned person to explain it to me.....HOPE one comes on here.....

Many other breeds have the black spots   on tongue, upper mouth roof, and  even on stomach , pads of their feet...but look how they got there.....lots of inbreeding or mixed bloodlines of various colors put in the MIX.
Kinda like  the CHEX

Red Sable

by Red Sable on 22 October 2010 - 17:10

That is one beautiful dog and beautiful little girl!!

yellowrose of Texas

by yellowrose of Texas on 22 October 2010 - 18:10

Yes , and I am glad the poster started this thread...

the white shepherd can be very pretty..and healthy....When I went to various sites last night I found some beautiful specimens of White Swiss shepherds ...very nice looking..very good body structure...and some working very well , also.

THERE are breeders in the Eastern part of the usa who have bred them for years , and have Schutz titles on them and show them and have many good reports on them.

I do not have any problem if that is their desire. As long as it is health and beauty and workability..I cannot tell you how many calls I have had for years and tales of the best gsd I ever had was a white gsd ,,and this was many years back, that they are speaking of...NOT current bred ones...

THe main remark I have heard for years from callers wanting another WHITE shepherd...was...ours was smarter than any dog we ever had,,a Gentle GIANT,   ,,more protective and could almost TALK>>>many tales of them killing snakes to protect an owner working in the garden or flower bed...one dragging a child out of a house,,,one keeping a woman from falling off a cliff...many tales of their loyalty...

YR






 


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