Renal insufficiency in young dog? - Page 1

They need t' be lookin' into gettin' this GSD Lassy on t' Anabolic Androgenic Steroid, Deca-Durabolin Aye! T' lassy will not come into season on t' AAS as well.

Has she/he been tested for Lyme Disease?

 Renal insufficiency can happen in a young dog sadly. When I hear distended abdomen I think liver not kidneys. Have they checked that? Either way, I don't think the future is bright for the young one. Temperament change could be kidneys or liver or many other things. Even in a country without sophisticated medical tools the vet should be able to percuss the abdomen to check the liver for fluid and palpate if the border is enlarged but if there is alot of fluid the border can be difficult to palpate even for a good vet which in and of itself should be diagnostic to some degree.Diuretics and antibiotics won't help if it's the liver but diuretics should help if it was kidneys. IMO i'm not a vet.

if you could get any details of the tests done or the blood work done it would help us to help your friend.

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JUVENILE RENAL DYSPLASIA (JRD) DNA TESTING
Discovery of the Mutation and development of a direct DNA test for JRD
by Dr. Mary H. Whiteley, Ph.D. - DOGenes Inc.
Read the article here
http://www.videxgsd.com/juvenile_renal_dysplasia_DNA_test.htm

THIS SHOULD INTEREST ALL GSD BREEDERS

And yes I agree, the future does not look bright for this young one.

The reason I mentioned Lyme Disease, is that if you are in a big Lyme disease area.  A dog being positive for Lyme Disease can cause renal failure.  And from what I've seen where Lyme disease does cause this, the outlook is very very very very poor.  We see a lot of Lyme disease where I work, mostly in the unvaccinated dogs for Lyme.  And a few, and only a very few go into Renal failure and it's very very sad, because there's really nothing that can be done at that point. 

Aye! if ye take t' GSD lassy to a University Vet College in t' US, they would be very knowledgable about the use of "Deca Durabolin"(nandrolone decanoate) regarding renal failure in Canines.  Your Vet should be able to find info and aquire t' drug easily aye. Me would give t' lassy 25mg per week for 6wks to start and then assess from there. Ye might even be able to get it at a Pharmacia. Me don't know t' laws or customs of ye country aye.

http://www.articlesltd.net/Article/Live-a-physically-active-life-with-Nandrolone-decanoate/1907

 oso if it is the liver and not the kidneys the steroids CaptMike mentioned would be harmful because they are metabolized by the liver. Please post the lab results when you get them.

In t' original post it was posted "diagnosed chronic renal insufficiency"......If several tests were performed, weren't common blood tests performed?aye Were HDL/LDL done?  A low plasma cholesterol level is indicative of severe liver disease. aye MCV (Mean Corpuscular Volume) A decrease in MCV would then indicate that t' RBC's are abnormally large(or macrocytic), and this may be an indicator of iron deficiency anemia or thalassemia. When an increase is noted, that would indicate abnormally small RBC (microcytic), and this may be indicative of a vitamin B12 or folic acid deficiency as well as liver disease. Glucose aye, Increased levels can be indicative of  chronic renal failure, Aye! BUN (Blood Urea Nitrogen)
This test measures t' amount of urea nitrogen that's present in t' blood. When protein is metabolized, t' end product is urea which is formed in t' liver and excreted from the bloodstream via the kidneys. This is why BUN is a good indicator of both liver and kidney function. aye Bilirubin, Bilirubin is one of t' many constituents of bile, which is formed in the liver. An increase in levels of bilirubin can be indicative of liver stress or damage/inflammation. AST (Aspartate Aminotransferase, previously known as SGOT) This is yet another enzyme that's used to determine if there's damage or stress to the liver. Aye! if ye canine has liver problems ye should give, Milk Thistle, ALA (Alpha Lipoic Acid), and  Liv-52 .

The ultra safe Deca injectable is (naturally) put right into the animal's (dog or human) bloodstream and only undergoes a far less extensive second pass metabolism. Aye! Proper dosage poses no problem to t' liver.

Reported Characteristics

• Pharmaceutical Name:Nandrolone Decanoate
• Chemical Name:19-nor-testosterone
• Cutting/Bulking:Both
• Anabolic Rating: 125
• Active-Life: 14-16 days
• Drug Class: Anabolic/Androgenic steroid
• Average Reported Dosage: Men 400-600mg weekly,  Women 50-100mg weekly
• Acne: Possible
• Water Retention: Some
• Decreases HPTA function: Severe
• High Blood Pressure: No.
• Aromatization: Low, converts to less active norestrogens
• Liver Toxic: No
• DHT Conversion: No, converts to NOR- DHT
• Noted Comments: Highly anabolic/moderate androgenic effects
• Average Price: 10/amp

Nandrolone Decanoate is a very anabolic and slightly androgenic form of 19-nortestosterone A very prominent positive nitrogen balance is realized with administration of this product. And since nandrolone promotes nitrogen storage, growthand repair in hard-trained muscles will bemore pronounced than normal. In addition, a noted effect by many athletes polled was that most of them  experienced a joint healing effect during Deca cycles. Since aromatization was low, in 400-600-mg weekly dosages, and fatburning was high due to the high affinity to the androgen recepror that Deca has, anti-estrogens were not typically necessary to avoid gyno and other estrogen induced side effects.

Commonly used doses for men were in the area of  400-600mg weekly, and dosages over 400 mgweekly caused more water retention, while women seemed to do well with 100mgs/week. In fact, women have consistently reported very respectable lean mass and strength gains at dosages of only 50-100 mg weekly. Virilizing effects usually were avoided by single weekly injections of 50-100 mg nandrolone decanoate. Men, however would need to stack Deca with testosterone in order to have more appreciable weight gains, and avoid sexula dysfunction.  Unfortunately, this compound is