DM testing - Page 6

Markobytes, thank you. That's what I am asking. Chan type disease be stopped by not breeding from a line that has produced dm dogs or is it something that really can't be eliminated? Are dog lines with it in its history more "prone" to it like people and cancer or is it a totally different thing.

I'm asking because I would like to breed my dog who is not a carrier but the dog I am interested in is a a/n which means her puppies could be clear or carriers but I am trying to see if I should pass on the sire for that reason. I really don't want to perpetuate a problem.

I am more familiar with horse breeding and there are devastating diseases that can be prevented if people would just not breed a carrier. These are known results in the horse world though. There is no maybe about it. The breeder I am talking to with the carrier has done her research on it. I am just looking to inform myself.

It all depends on who you agree with, jprony. Truth is Clemmons and the OFA testing lab have not been on the same page from day one and politics have played a big role for each of them. Is it any wonder the DM process remains status quo? Once again, the dogs have taken a back seat to human egos.

If you decide the DNA test is valid and if you breed your "normal" female to a "carrier" about one half of the litter will test as normals; one half as carriers; none will test at risk for developing DM. If you decide that DNA testing isn't valid, then it really won't matter which male you choose for your female. A carrier can only produce an at risk if bred to another carrier or an at risk. DM must come from both parents.

Jprony, under the guidelines of the test you are being responsible, but there is no substitute for knowing the lines as much as possible and what they produce. How confident are you that you can find homes for say, eleven puppies? One of the problems you may face is losing buyers who don't want the chance of having a carrier of DM. This problem is made worse by people who are unwilling or unable to educate what the test really means.
Contrary to popular belief, DM can come in different forms, each with its own symptoms, and probably it's own causes. The test was developed with research into the form that afflicts Corgis and Boxers, GSDs that have DM seem to have a different form, with a different manifestation and maybe a different cause. I am not convinced that a variant in a gene is responsible for all forms of DM in all breeds.
What is sure is that it is irresponsible to infer that a dog is clear or free of DM based on results of this test.

It's not fair to label a breeder as irresponsible just because he or she believes that the DM test is valid and that they are being honest when they tell buyers that their DNA normal pup won't develop DM. 

Wow, that statement seems to fly in the face of science and the research.

Jprony, i forgot to mention that I would not exclude this stud, you have to be aware and educate the potential buyers if they have a concern.

What is sure is that it is irresponsible to infer that a dog is clear or free of DM based on results of this test.

Most everyone here has read enough already about DM and the DNA testing and is smart enough to be able to make up their own minds if they want to test/ need to test and how to represent those results to their buyers.  No matter what that decision, none deserve to be called irresponsible.