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by Nancy on 08 March 2012 - 12:03
Update my dog, Grim van der woude tested "Carrier" and FWIW the U of M report that came *did* indicate some dogs with the "Carrier" test results have been diagnosed with DM. As is for him, we are still pursuing options - slight improvement - actually the only thing I really see now is that is foot tends to "drag" under him a little bit when he is making a sharp turn and he "catches" himself and does not almost fall anymore. Hocks more stable. he flips his foot..
planning to see a holistic vet before subjecting him to more invasive diagnostic procedures.
Grim is WL, Czech -
planning to see a holistic vet before subjecting him to more invasive diagnostic procedures.
Grim is WL, Czech -
by Blitzen on 08 March 2012 - 13:03
Nancy, maybe you dog doesn't have DM?
by Smiley on 08 March 2012 - 13:03
Have any dogs with DM ever been tested Normal/normal through OFA? I ask as my bitch came back normal/normal (east german bloodlines) and now I am really worried that the test was somehow inaccurate?
Or, is it appearing the double normals are clear and the carriers *might* develop DM along with the actives?
Thanks,
Sara
Or, is it appearing the double normals are clear and the carriers *might* develop DM along with the actives?
Thanks,
Sara
by Nancy on 08 March 2012 - 15:03
I just reported the results - you don't really know if it is DM until the end....Just that the report from U of M indicated a possiblity with carrier designation.
by desertstorm3115 on 08 March 2012 - 16:03
Our baby was a carrier with OFA n/c & Affected with DDC a/a. We lost her at a young age, we put her down when the signs where there. I was not going to let my wife be selfish when we saw her toe dragging ect ect. We gave her a good week, let her do what she wanted and then put her down.
This is all I am going to say about this, it is just to painful to watch back yard breeders not test their dogs then sell them at a high price not caring about the welfare of the dog or the feelings of others. I feel that any dog that tests for this, the breeder should be made aware of this problem.
If they continue to breed it shows you who their true character.
This is all I am going to say about this, it is just to painful to watch back yard breeders not test their dogs then sell them at a high price not caring about the welfare of the dog or the feelings of others. I feel that any dog that tests for this, the breeder should be made aware of this problem.
If they continue to breed it shows you who their true character.
by Nancy on 08 March 2012 - 22:03
Ddc?
by Abby Normal on 08 March 2012 - 23:03
Nancy
Can you be a little clearer about what the UofM actually said about some carrier dogs having been diagnosed with active DM?. It is just that there is some growing speculation around this and if you have a statement from them in your report it would be very helpful to know what it actually says.
As Blitzen says, it could be your dog does not have DM. I have never yet heard of a case of DM improving. I do hope that this is the case and it turns out your dog doesn't have DM.
Sara
There has been doubt cast by some about this test, but much of this is hearsay and speculation. What is lacking at the moment is the factual evidence to support it. I think it would be a great idea to contact the UofM and ask them your question directly. It would be very useful to be able to report that answer back to this thread, so that we can have factual information, from the horses mouth so to speak on this important issue. It may also help to set your mind at rest.
Can you be a little clearer about what the UofM actually said about some carrier dogs having been diagnosed with active DM?. It is just that there is some growing speculation around this and if you have a statement from them in your report it would be very helpful to know what it actually says.
As Blitzen says, it could be your dog does not have DM. I have never yet heard of a case of DM improving. I do hope that this is the case and it turns out your dog doesn't have DM.
Sara
There has been doubt cast by some about this test, but much of this is hearsay and speculation. What is lacking at the moment is the factual evidence to support it. I think it would be a great idea to contact the UofM and ask them your question directly. It would be very useful to be able to report that answer back to this thread, so that we can have factual information, from the horses mouth so to speak on this important issue. It may also help to set your mind at rest.
by Smiley on 09 March 2012 - 02:03
Ok, Abby. I'll ask and let everyone know....
Sara
Sara
by Nancy on 09 March 2012 - 02:03
This is copy and paste from the report-it came directly from the University as the Vet clinic went through them and not OFA so I have to send the report to OFA which I will.
What they have not done is provide an explanation how a carrier can get DM and a Normal cannot. I think what this is really saying is they have not encountered a Normal WITH DM yet. It would be good to understand by what mechanism they would speculate a carrier would be able to get the disease.
I am putting my own energy into looking into other sources of the problem, not a topic for this particular thread so I will not digress.
This is in reference to an acknowledgement that they have had a few carrier dogs wind up with DM-and the request for the statement in the report....actually you can go to the University of Missouri web page and they report the two "carriers" who were diagnosed with DM....so it is definitely out there.
-----
Grim tested CARRIER
Brief explanation of results;
NORMAL dogs are not at risk for developing DM and can safely be bred to a dog with any test result.
CARRIER are far less likely to develop DM, but we have confirmed DM in a few carrier dogs. They may be used carefully in breeding programs to keep their good qualities while reducing risk of DM in future generations.
AFFECTED dogs are AT RISK for developing DM at some point in their lifetime. Not all AFFECTED/AT RISK dogs develop observable clinical symptoms. At present we do not a way to predict when clinical symptoms may appear. Additional research is underway to help determine these details.
Dogs testing NORMAL or CARRIER who exhibit symptoms suggestive of DM should have additional diagnostics done to determine the possible underlying cause of observed symptoms.
What they have not done is provide an explanation how a carrier can get DM and a Normal cannot. I think what this is really saying is they have not encountered a Normal WITH DM yet. It would be good to understand by what mechanism they would speculate a carrier would be able to get the disease.
I am putting my own energy into looking into other sources of the problem, not a topic for this particular thread so I will not digress.
This is in reference to an acknowledgement that they have had a few carrier dogs wind up with DM-and the request for the statement in the report....actually you can go to the University of Missouri web page and they report the two "carriers" who were diagnosed with DM....so it is definitely out there.
-----
Grim tested CARRIER
Brief explanation of results;
NORMAL dogs are not at risk for developing DM and can safely be bred to a dog with any test result.
CARRIER are far less likely to develop DM, but we have confirmed DM in a few carrier dogs. They may be used carefully in breeding programs to keep their good qualities while reducing risk of DM in future generations.
AFFECTED dogs are AT RISK for developing DM at some point in their lifetime. Not all AFFECTED/AT RISK dogs develop observable clinical symptoms. At present we do not a way to predict when clinical symptoms may appear. Additional research is underway to help determine these details.
Dogs testing NORMAL or CARRIER who exhibit symptoms suggestive of DM should have additional diagnostics done to determine the possible underlying cause of observed symptoms.
by Abby Normal on 09 March 2012 - 08:03
Nancy
Thank you very much for that, it is very helpful. Good luck with Grim, and I hope it turns out to be something other than DM, that you can work with.
Sara, I look forward to hearing what the UofM say. I think Nancy probably has answered the question with her post above which is from her report from the UofM, but it does no harm to ask these questions, as things are always developing in the area of scientific discovery.
Thank you very much for that, it is very helpful. Good luck with Grim, and I hope it turns out to be something other than DM, that you can work with.
Sara, I look forward to hearing what the UofM say. I think Nancy probably has answered the question with her post above which is from her report from the UofM, but it does no harm to ask these questions, as things are always developing in the area of scientific discovery.
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