INHERITED DISEASES IN DOGS - Page 3

Pedigree Database

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Kaffirdog

by Kaffirdog on 24 August 2010 - 17:08

I would have liked to see some indication of the frequency these diseases have been seen, there is no indication of whether or not there have been numerous cases or if just one case is enough to put a disease on the list..

Margaret N-J

Abby Normal

by Abby Normal on 24 August 2010 - 18:08

   I think you're right MissB, I think the BC was collating a health database but it fell by the wayside I don't remember who was collating the information. Do you know MissB, if I had enough knowledge about computers, and websites I would truly love to do it. I would probably need to wait for my 'formal' retirement as well tho'. But if it isn't being done by then, I will promise I will happily step forward and offer my services.

However, the BC, and the GSDL as representative of the breed have websites already which could easily have a page dedicated to this purpose. Perhaps if they are already collating the information the GSD Information group could do it.  It will be wonderful if they have found a genetic marker for AF, so long as breeders subsequently use any test that becomes available. Then legitimate results of a registered genetic test could be registered, which may do away with the need for a vet letter. Who is doing the research LilyD?

Agree LilyDexter, it would have to be thought through carefully, but with the great minds at disposal on this board and in breed clubs etc I am sure it would be a cinch. To be a little more radical a salary for a collator could be funded by active breeders, along with donations from any interested person to the GSDL for the purpose.  

In respect of being put off using lines even though they have some bad points, agreed - that is where you really need someone like Malcolm Willis, but until you know the size of a problem it is hard to say what impact it may or may not have.  However the current pedigree researchers work on an element of 'risk analysis' now don't they. They don't say 'avoid' they say the risk from these lines or this mating is XXX It is surely just an extrapolation of that risk assessment. Food for thought.

by kimbailey on 24 August 2010 - 23:08

It seems to miss glaucoma out in Border Collies so not sure just how accurate, plus they include coat length for them, it's black and solid in GSDs...how bizarre to treat these issues as 'diseases'. Glaucoma is a 'new' problem in border collies, but it is there and it is believed to be hereditary. They have lots of problems within the breed, epilepsy is a major one. With Glaucoma and TNS there is more openness and this is a huge advantage with two 'new' (not really!) diseases, fortunately there are tests for the propensity for Glaucoma (narrow angle drainage type anyway) and DNA test for TNS. Interestingly this was initially felt to be an 'Australasian' issue, but now with DNA testing is is fairly widespread amongst British dogs (no wonder this is where they came from originally). There does seem a lot of secrecy over epilepsy unfortunately.

Abby Normal

by Abby Normal on 25 August 2010 - 09:08

@ Margaret N-J, this is what the body text says:
At present the site is restricted to diseases that have been documented in the peer reviewed scientific literature or through breed or disease registries. To be included a disease must either show a clearly familial pattern of occurrence or a clear breed predisposition, as evidenced by a markedly increased odds ratio (OR > 5, or as stated in the table) of the disease occurring in that breed, when compared with the general dog population. For a number of commoner defects (hip dysplasia, elbow luxation and some others) which occur in many breeds, we have arbitrarily chosen to record the 20 breeds with the highest breed prevalence as recorded in open registries. Hence, the lists of diseases are necessarily incomplete - and the level of occurrence of each listed disease varies from common to very rare.

Bearing in mind the controversy over the conformation of the GSD, this was interesting:
This report has shown that every one of the 50 most popular pedigree breeds of dog in the UK were found to have at least one aspect of their physical conformation predisposing it to a heritable defect.

@ Kim Bailey
I am guessing that this list is not completely up to date, as the Glaucoma issue in BC's is *relatively* new (new being a relative term). Unfortunately there is no indication as to the date of the article, my only criticism of some articles on various websites. It would be very useful if those who post articles on websites by external bodies/individuals), date that information as it can be crucial to the context, and also to account for what may have occurred since it was written?

Epilepsy is an issue which seems to be shrouded in secrecy in all breeds sadly. 

Videx

by Videx on 26 August 2010 - 00:08

 look again

Abby Normal

by Abby Normal on 26 August 2010 - 09:08

At what?


Videx

by Videx on 26 August 2010 - 15:08

 dates 

Abby Normal

by Abby Normal on 26 August 2010 - 15:08

Ah there you go Kim - 2004.

by kimbailey on 01 September 2010 - 13:09

Yes thanks, missed the date, this would explain absence of glaucoma, but also what else?  It was an interesting posting (I'm not moaning!) but it would be useful to know of stuff arrising between then and now.

Prager

by Prager on 03 September 2010 - 19:09

So the black color is a disease?
Prager Hans
http://www.alpinek9.com





 


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