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by Rottiegirl on 09 October 2012 - 18:10
Hi. I have a 2 1/2 year old and 12 week old Rottweilers. I am currently using Ivermectin for my 85 lb female for treatment of Heartworms. We just brought home her little brother (same parents bred 2 1/2 years later) and are having some issues with worms. I have researched that Safeguard 10 Suspension is safe to use for worming purposes at 1ml per 5 lbs. Is it safe to use with Ivermectin at this dosage? I will not be dosing the puppy with Ivermectin until he is 6 months old. I just wanted to dose my older Rottie just to keep her clean from the little guys worms. Any insight would be greatly appreciated. Thanks in advance!
by B.Andersen on 09 October 2012 - 20:10
Safequard 10 percent is used at 1.0 ml per 5 lbs. Liquid Ivermectin is used at .1 ml per 10 lbs that is .1 not 1.0 ml!

by BlackthornGSD on 09 October 2012 - 20:10
Safeguard and Ivermectrin are very different drugs. I suggest getting Safeguard for de-worming of intestinal parasites. (HW are not an intestinal parasite.) You can get Safeguard/Panacure/febendazole for very reasonable prices online or at your local feedstore.
If you are treating an actual HW infection with that dosage, the dose must be much higher than the dose used as a preventive.
The Ivomec dose for prevention is closer to 0.1 cc per 10 pounds. Please consult your vet.
If you are treating an actual HW infection with that dosage, the dose must be much higher than the dose used as a preventive.
The Ivomec dose for prevention is closer to 0.1 cc per 10 pounds. Please consult your vet.

by VKGSDs on 09 October 2012 - 20:10
Are you trying to "prevent" heartworms or treat a dog that already has them?
As a preventative, 1% ivermectin at .1mL per 10lbs is still quite high. I give my 65-65lb dogs .25mL and this is still much, much higher dose than a Heartgard tablet (I believe about 8x as high but I'm looking for my document that has the math....). Because different forms have different concentrations you have to look at the actual micrograms per pound.
*Found my math as well as a spreadsheet sent to me by someone else and both show that it looks like a Heartgard dose of 1% ivermectin is about 0.020mL for a 75lb dog.
As a preventative, 1% ivermectin at .1mL per 10lbs is still quite high. I give my 65-65lb dogs .25mL and this is still much, much higher dose than a Heartgard tablet (I believe about 8x as high but I'm looking for my document that has the math....). Because different forms have different concentrations you have to look at the actual micrograms per pound.
*Found my math as well as a spreadsheet sent to me by someone else and both show that it looks like a Heartgard dose of 1% ivermectin is about 0.020mL for a 75lb dog.

by Rottiegirl on 10 October 2012 - 12:10
Thank you for the responses. I am using the Ivermectin as a preventative. My girl gets .85ml every month. My dogs are heartworm free. I've been using the Ivermectin for my girl for quite a while now. Fully aware that HW's are not intestinal parasites. Was just wondering if it was safe to mix the two. I don't want to hurt her. I've just never tried the SafeGuard other then in pill/powder form specifically for dogs. I was looking to get the suspension for goats to give to my new boy for treatment of worms and then biannually as preventative for both of them. I have him on the SafeGuard powder right now and hopefully that will kick the parasites out!

by Rottiegirl on 10 October 2012 - 12:10
@VKGSDs, My vets are the ones that gave me the .1ml per 10 lb weight for my girl. I was dosing her at half that when we revisited her heartworm preventative. She told me to gradually bring her up to to this dosage. She's had no adverse reactions or side affects to the larger dose.

by VKGSDs on 10 October 2012 - 13:10
Oh I agree it's a perfectly safe dose (there is a HUGE range of dosing for ivermectin) but not always necessary. That dose is 37 times stronger than a Heartgard tablet. I personally don't think the tablets are strong enough anymore. I'm guessing the dose is low so that the company avoids deaths due to MDR-1 gene problems and people not testing those dogs first. I'm comfortable dosing 8-10 times stronger than Heartgard and none of my dogs have ever had heartworm (I test every April). If I don't have to dose higher than that to prevent heartworm then I'd rather not give the dogs any more chemical than necessary and have my vial last longer.
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