LynOD, what brand of Glucosamine and Chondroitin are you using? This is actually a very important detail that many do not consider. There was a great study done from the perspective of horse supplements and the findings basically said Nutramax (Cosequin) was one of the few brands that had true quality control of thier end product. If you haven't started using Cosequin or Dasaquin, I recommend that you do and be sure what is causing the poor results. As I said above Animal Health Options also has very good quality control on thier animal supplement products. As for the stem cell procedure, did you use medi-vet or vet-stem? The medi-vet method separates the stem cell at the vets office, vet stem uses a frozen by mail process. My vet doesn't recommend stem cell treatment, but it was his opinion that separating the stem cell on site would have a much better result. At one point I consulted a race horse vet on his experience with stem cells and he said it needs to be done with a few other treatments to have a drastic overall effect and also may need to be done multiple times for full effect. Also the stem cell process dogs get is not the same as the one horses are getting. The horse stem cell treatment offered by vet-stem uses bone-marrow stem cells, but the dog version gets it sample from fat cells. My vet says at best the fat stem cells will act as longer lasting lubricants in a way that is similar to Adequan, however unlike the bone-marrow stem cells they will never turn into anything that can heal existing damage. I don't know why they do this because a professor at UC Davis is using stem cells from dog bone marrow successfully to reduce the effects of DM. If dog stem cell treatments were done like race horses with bone-marrow, the results would be dramatic. Its almost like the fat cell stem cell treatment is a quick scam money generator for Vet-stem.
After talking with horse vets that use the Tidren brand of bisphosphonate, I believe it could be a viable option for dog with HD and bad arthritis. However, online most people are talking about using it with cancer treatments for dogs, which is surprising to me becuase if you look up how bisphosphonates are used for horses it is ALWAYS used to help with lamness and arthritis. Why no one is talking about using it for dogs arthritis is beyond me:
Here is a dog article that briefly mentions using bisphosphonate to stabilize bone and managing pain, but then goes off into left field with a discussion about dog cancer:
My vet said that the bisphosphonate should be given by IV, however I have read that regional profusion repeated 3 times at 2 week intervals will work better and will also prevent the animal from feeling sick. Suppossedly, 3 doses administered directly to the site of the injury is better than 10 doses administered to the whole body systematicaly. Who knows though because this info all comes from horse people.